Amphetamines should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Sudden death has been reported in patients with structural cardiac abnormalities or other serious cardiac disease who were treated with CNS stimulant treatment at the recommended ADHD dosages. Chlorpromazine blocks dopamine and norepinephrine receptors, thus inhibiting the central stimulant effects of amphetamines, and can be used to treat amphetamine poisoning. May enhance the activity of tricyclic or sympathomimetic agents causing striking and sustained increases in the concentration of d-amphetamine in the brain; cardiovascular effects can be potentiated.
What is Adderall’s dosage?
Infants born to mothers dependent on amphetamines have an increased risk of premature delivery and low birth weight. Also, these infants may experience symptoms of withdrawal as demonstrated by dysphoria, including agitation, and significant lassitude. CNS stimulants, at recommended doses, may cause psychotic or manic symptoms (e.g., hallucinations, delusional thinking, or mania) in patients without a prior history of psychotic illness or mania. If such symptoms occur, consider discontinuing ADDERALL. CNS stimulants cause an increase in blood pressure (mean increase about 2 to 4 mm Hg) and heart rate (mean increase about 3 to 6 bpm). Monitor all ADDERALL-treated patients for potential tachycardia and hypertension.
Tell your health care provider if you have ever misused alcohol, prescription medicines, or street drugs. Amphetamine/dextroamphetamine is a controlled substance and may be misused. Tell your health care provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them determine if amphetamine/dextroamphetamine is right for you. Serotonin syndrome is when there is too much of a substance called serotonin in your body.
Do not take amphetamine/dextroamphetamine unless it has been prescribed to you by a health care provider. Amphetamine/dextroamphetamine should not be taken while you are using certain other medicines. Before taking amphetamine/dextroamphetamine, tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. Some people who have taken amphetamine/dextroamphetamine have reported having seizures. There are many different types of seizures and some of them are not easy to recognize.
- However, avoid taking Adderall late in the afternoon or evening.
- Your doctor or pharmacist can tell you more about the potential side effects of Adderall.
- This may raise your risk of side effects such as insomnia (trouble sleeping), nervousness, and anxiety.
- The anorectic and stimulatory effects of amphetamines may be inhibited by lithium carbonate.
Call your health care provider right away if you have any new or worsening tics. You may take it once, twice, or sometimes three times a day. You should take your first dose when you first wake up in the morning. Then, you’ll take any further doses every 4 to 6 hours. In some people, Adderall can reduce blood flow to the fingers or toes. If you already have a condition that causes reduced blood circulation in your fingers and toes, such as Raynaud’s phenomenon, you may have a higher risk of this side effect.
The lists below describe some of the more common side effects that Adderall may cause. These lists don’t include all possible side effects. These generic medications come in two primary types, immediate release (IR) and extended release (XR), and are manufactuered by many different pharmacutical companies. You are encouraged to report negative side effects of prescription drugs to the FDA. Talk to your healthcare provider if you or your child have side effects that are bothersome or do not go away.
Does amphetamine/dextroamphetamine interact with foods or drinks?
If you have trouble swallowing capsules or tablets, see this article for tips on how to swallow these forms of medication. Your first Adderall tablet dose of the day should be taken when you first wake up. If your doctor recommends it, you may take one or two additional doses throughout the day separated by 4 to 6 hours. However, avoid taking Adderall late in the afternoon or evening.
- Take amphetamine/dextroamphetamine exactly as prescribed.
- Tell your health care provider about all medicines that you take or have recently taken.
- Tell your health care provider if you have ever misused alcohol, prescription medicines, or street drugs.
- But if you think you’re having a medical emergency, call 911 or your local emergency number.
- Talk with your doctor before stopping Adderall treatment.
How does Adderall compare with similar drugs, such as Ritalin?
This is important to do because some medications can interact with Adderall. Medicare Part D or Medicare Advantage (Part C) plans may cover both brand-name and generic Adderall. Adderall starts working within 1 to 2 hours after you take a dose. Adderall and other stimulants have some similarities and some differences. Call your doctor right away if you have an allergic reaction to Adderall.
Does amphetamine/dextroamphetamine interact with other medicines (drug interactions)?
Talk with your child’s doctor if you have questions about their dosage. For the remainder of this article, the term “Adderall” refers to both forms of the drug except where specified. Your pharmacist can tell you all of the ingredients in the specific amphetamine/dextroamphetamine products they stock. Amphetamine/dextroamphetamine should be stored at room temperature, between 68 F and 77 F (20 C and 25 C).
The coadministration with cytochrome P450 (CYP2D6) inhibitors increase the risk with increased exposure to ADDERALL. In these situations, consider an alternative nonserotonergic drug or an alternative drug that does not inhibit CYP2D6 see DRUG INTERACTIONS. Misusing Adderall can cause serious side effects, including heart problems and even sudden death. (With dependence, your body needs a drug to function as usual.) The risk of dependence is higher if you take Adderall long term, even if you take it as your doctor prescribed it.
What Drugs, Substances, or Supplements Interact with Adderall?
In general, doctors usually prescribe methylphenidate for ADHD in children and amphetamine-based stimulants for ADHD in adults. If stimulants cause troublesome side effects or don’t work well enough, doctors may prescribe a nonstimulant drug for ADHD. Examples of nonstimulant drugs include atomoxetine (Strattera) and guanfacine (Intuniv). Before prescribing ADDERALL, assess each patient’s risk for abuse, misuse, and addiction. Educate patients and their families about these risks and proper disposal of any unused drug. Advise patients to store amphetamine sulfate in a safe place, preferably locked, and instruct patients to not give ADDERALL to anyone else.
Long-Term Suppression Of Growth In Pediatric Patients
There are no known interactions between amphetamine/dextroamphetamine and foods or drinks. Some forms of amphetamine/dextroamphetamine can be taken with or without food but may need to be taken the same way each time. Ask your pharmacist or another health care provider how to take the amphetamine/dextroamphetamine form you are prescribed. People who have serious heart disease or heart defects may be at risk of sudden death if they take amphetamine/dextroamphetamine. Tell your health care provider if you have any heart problems, including heart disease, heart defects, cardiomyopathy, or an abnormal heart rhythm (arrhythmia).
If you drink alcohol, talk with your doctor about how much (if any) is safe to drink during your Adderall treatment. You should not drink alcohol during your Adderall treatment. Adderall can mask the effects of alcohol, so you may drink more than you usually would. In some cases, this could lead to alcohol poisoning. If you have a condition that causes seizures, such as epilepsy, Adderall could make your condition worse. If you adderall long term side effects have tics or Tourette syndrome, Adderall could make your condition worse.
Call your healthcare provider right away if you have or your child have any signs of unexplained wounds appearing on fingers or toes during treatment with ADDERALL. Tell your healthcare provider about any mental problems you or your child have or about a family history of suicide, bipolar illness, or depression. Amphetamine is known to inhibit monoamine oxidase, whereas the ability of amphetamine and its metabolites to inhibit various P450 isozymes and other enzymes has not been adequately elucidated. In vitro experiments with human microsomes indicate minor inhibition of CYP2D6 by amphetamine and minor inhibition of CYP1A2, 2D6, and 3A4 by one or more metabolites.
There are multiple forms of amphetamine/dextroamphetamine available. They may be used to treat different conditions and are taken in different ways. Read and follow the instructions for the product you have and make sure you understand how to prepare, take, and throw it away properly. If you have any questions, talk to your health care provider. Keep amphetamine/dextroamphetamine out of the reach of children.
